Senior Associate Scientist - Dublin , Ireland - Pfizer

Description

Application Closing date:14 April 2024

Job Purpose:

Antibody engineering and screening sciences within a nimble (multi-project) and cutting-edge biotherapeutic discovery team in our Display-based Optimisation Group which is part of the global Biomedicine Design (BMD) team. Our laboratory is located at Grange Castle in Dublin, Ireland and focuses on the application of advanced protein engineering technologies towards the discovery and optimisation of novel protein therapeutics, with a particular emphasis on monoclonal antibodies. Pfizer is a leader in the development of protein biopharmaceuticals and has a successful track record of multiple product approvals in Oncology, Inflammation, Rare Diseases and Cardiovascular disease. This is an exciting opportunity to join a team in a world-class organisation dedicated to the application of industry-leading science for treatment of significant unmet medical needs. Applicants for this position should clearly highlight their relevant experience and qualifications which make them directly suited to this role.

Job Responsibilities:

• Perform antibody discovery and engineering work (including phage & yeast display technologies, antibody library construction and selection, functional screening and reformatting of key leads), within a matrixed team of researchers.
• Perform troubleshooting and resolution of experimental issues.
• Facilitate cross-functional project teams internally within PDOG, across BMD and between BMD and Pfizer R&D research units (RUs).
• Implement effective technology development & continuous process development to ensure success on drug discovery programs.
• Develop and maintain productive links with colleagues across R&D, and in the external scientific community, to maintain current information, skills and knowledge in the BMD.

Education/Experience:

• Minimum qualification BSc or MSc degree in Molecular Biology, Biotechnology or equivalent relevant discipline.
• Experience in a biotechnology/biochemistry research environment is preferred.
• The position will require proven molecular biology skills (i.e. DNA/RNA isolation, PCR, DNA manipulation and transformation).
• Previous experience with bacterial and/or mammalian expression systems and protein purification is desirable.
• Some experience with high-throughput automation is an advantage.
• Functional knowledge and experience of protein display technologies and the use of recombinant antibody libraries is preferred.
• Proven ability to organise and conduct experimental research.

Work Location Assignment: On Premise

Additional Information

• In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland.
• Please note there is no relocation support available for this position

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How to apply

• Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you

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Purpose

Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.

Digital Transformation Strategy

One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.

Equal Employment Opportunity

We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees.